For nearly all d20 rolls, a natural roll (meaning the unmodified number that comes up on the die) of a 1 or 20 will have some special significance. A natural 1 will almost always be a failed roll no matter the modifiers and a natural 20 will almost always be a success. That does not mean, however, that a character can request to do anything and then if they get a 20 it is a success. Their action has to be possible within the context of the situation.